Development and external validation of a nomogram to predict prolonged postoperative mechanical ventilation in patients with acute type A aortic dissection - Takeaways - MDSpire

Development and external validation of a nomogram to predict prolonged postoperative mechanical ventilation in patients with acute type A aortic dissection

  • By

  • Qi Yue

  • Jianhao Hu

  • Xin Li

  • Haiyuan Liu

  • Zhenxiao Ma

  • Chun Wu

  • Weibo Kong

  • Yuyong Liu

  • July 8, 2026

  • 0 min

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  • 1

    A nomogram was developed to predict prolonged mechanical ventilation (PMV) in patients undergoing surgery for acute type A aortic dissection (ATAAD).

  • 2

    The study included 479 ATAAD patients for model training and 120 for external validation, adhering to TRIPOD guidelines.

  • 3

    Ten predictors were identified, including age, preoperative serum albumin, and aortic cross-clamp time, with significant odds ratios.

  • 4

    The nomogram demonstrated good discriminatory ability with AUC values of 0.796 for training and 0.765 for validation cohorts.

  • 5

    At optimal cutoff values, the nomogram achieved sensitivity and specificity rates of 78.6% and 66.7% in the training cohort, respectively.

Original Source(s)

Development and external validation of a nomogram to predict prolonged postoperative mechanical ventilation in patients with acute type A aortic dissection

  • by Qi Yue, Jianhao Hu, Xin Li, Haiyuan Liu, Zhenxiao Ma, Chun Wu, Weibo Kong, Yuyong Liu

  • July 8, 2026

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