An online nomogram based on bimodal ultrasound images for preoperative diagnosis of cytologically indeterminate thyroid nodules - Takeaways - MDSpire

An online nomogram based on bimodal ultrasound images for preoperative diagnosis of cytologically indeterminate thyroid nodules

  • By

  • Wenwu Lu

  • Di Zhang

  • Xin Wu

  • Wenbo Ding

  • Xiang Xie

  • Lei Hu

  • Lei Ye

  • Wang Zhou

  • Chaoxue Zhang

  • June 29, 2026

  • 0 min

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  • 1

    The study developed an online nomogram for preoperative assessment of malignancy risk in cytologically indeterminate thyroid nodules.

  • 2

    Multimodal imaging features, genetic testing, and elastography levels were identified as key markers for diagnosing indeterminate thyroid nodules.

  • 3

    The nomogram demonstrated strong performance with an area under the curve of 0.907 in the training set and 0.860 in the prospective validation set.

  • 4

    The model integrates B-mode ultrasound, strain elastography, and molecular testing data to improve malignancy risk assessment.

  • 5

    This approach aims to reduce unnecessary diagnostic thyroidectomies and support more precise clinical decision-making for patients.

Original Source(s)

An online nomogram based on bimodal ultrasound images for preoperative diagnosis of cytologically indeterminate thyroid nodules

  • by Wenwu Lu, Di Zhang, Xin Wu, Wenbo Ding, Xiang Xie, Lei Hu, Lei Ye, Wang Zhou, Chaoxue Zhang

  • June 29, 2026

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