Long-term Sequelae Following Dengue Infection vs SARS-CoV-2 Infection in a Pediatric Population: A Retrospective Cohort Study - Takeaways - MDSpire

Long-term Sequelae Following Dengue Infection vs SARS-CoV-2 Infection in a Pediatric Population: A Retrospective Cohort Study

  • By

  • Liang En Wee

  • Jue Tao Lim

  • Janice Yu Jin Tan

  • Calvin Chiew

  • Chee-Fu Yung

  • Chia Yin Chong

  • David Chien Lye

  • Kelvin Bryan Tan

  • March 7, 2025

  • 0 min

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  • 1

    This study compared long-term complications in children after dengue and SARS-CoV-2 infections in a multiethnic Singaporean population.

  • 2

    Children with dengue showed a higher risk of gastrointestinal sequelae, particularly appendicitis, compared to those with SARS-CoV-2 infection.

  • 3

    Overall, dengue infection was associated with a lower risk of postacute complications compared to COVID-19 in the studied pediatric population.

  • 4

    The study utilized national registries to construct cohorts of children aged 1 to 17 years with confirmed dengue or SARS-CoV-2 infections.

  • 5

    Public health strategies should address the potential for chronic postinfectious sequelae following both dengue and COVID-19 infections in children.

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