The Relationship Between Personality Traits and Alzheimer's Disease: A Narrative Review - Takeaways - MDSpire

The Relationship Between Personality Traits and Alzheimer's Disease: A Narrative Review

  • By

  • Bednorz, Adam

  • Religa, Dorota

  • May 6, 2026

  • 0 min

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  • 1

    High neuroticism is consistently linked to an increased risk of Alzheimer's disease and accelerated cognitive decline.

  • 2

    Low conscientiousness is associated with a greater risk of Alzheimer's disease, influencing its onset and progression.

  • 3

    Conscientiousness may provide a protective effect against cognitive decline, mediated by health-related behaviors.

  • 4

    Extraversion and openness have variable associations with Alzheimer's, potentially offering protective roles through social engagement.

  • 5

    Longitudinal studies indicate personality traits serve as premorbid risk factors for Alzheimer's rather than reflecting disease changes.

Original Source(s)

The Relationship Between Personality Traits and Alzheimer's Disease: A Narrative Review

  • by Bednorz, Adam , Religa, Dorota

  • May 6, 2026

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