Toward personalized medicine for mal de débarquement syndrome - Takeaways - MDSpire

Toward personalized medicine for mal de débarquement syndrome

  • By

  • Jun Maruta

  • Catherine Cho

  • Sergei B. Yakushin

  • June 22, 2026

  • 0 min

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  • 1

    Mal de débarquement syndrome (MdDS) is a chronic vestibular disorder characterized by persistent non-spinning vertigo and various somatic, cognitive, and affective symptoms.

  • 2

    The etiology of MdDS is unclear, but it may involve maladapted neuroplasticity in the central vestibular system's velocity storage mechanism.

  • 3

    Two treatment approaches targeting velocity storage have been explored: VOR readaptation and velocity storage attenuation, with varying success rates.

  • 4

    Individual variations in symptom presentation may influence the perceived severity of MdDS and the effectiveness of treatment approaches.

  • 5

    The assessment of treatment efficacy relies on self-reported overall severity of MdDS, which is complicated by the subjective nature of symptoms.

Original Source(s)

Toward personalized medicine for mal de débarquement syndrome

  • by Jun Maruta, Catherine Cho, Sergei B. Yakushin

  • June 22, 2026

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