Trimodal Treatment Approaches for Inflammatory Breast Cancer - Takeaways - MDSpire

Trimodal Treatment Approaches for Inflammatory Breast Cancer

  • By

  • Audree B. Tadros

  • Risa Kiernan

  • April 9, 2026

  • 0 min

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  • 1

    Inflammatory breast cancer (IBC) has a 5-year survival rate of 55% to 70% without distant metastasis at presentation.

  • 2

    Trimodal therapy (TMT) improves survival outcomes for IBC patients but its use declined to less than 25% by 2020.

  • 3

    IBC patients exhibit worse survival rates compared to those with non-IBC locally advanced breast cancer.

  • 4

    Only 25.1% of IBC patients received guideline-concordant care, with many not undergoing appropriate surgical management.

  • 5

    Adherence to guideline-concordant care and exploring innovative treatments like neoadjuvant radiotherapy are crucial for improving IBC outcomes.

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