Susceptibility- and T2*-weighted MRI features of CNS large B-cell lymphoma in a large single-center cohort: prevalence, patterns, and clinical associations - Takeaways - MDSpire

Susceptibility- and T2*-weighted MRI features of CNS large B-cell lymphoma in a large single-center cohort: prevalence, patterns, and clinical associations

  • By

  • Christophe T. Arendt

  • Marie Löhlau

  • Linda Röder

  • Michael C. Burger

  • Elke Hattingen

  • Stefan Weidauer

  • July 12, 2025

  • 0 min

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  • 1

    Lymphomas are the second most common primary malignant CNS tumors in adults, with primary diffuse large B-cell lymphoma being the most prevalent subtype.

  • 2

    Neuroradiological features are essential for differentiating CNS lymphomas from other tumors, particularly to avoid corticosteroid use before biopsy.

  • 3

    Susceptibility effects on T2*-weighted MRI can appear in up to 50% of primary diffuse large B-cell lymphoma cases, contrary to earlier beliefs.

  • 4

    The study analyzed a large cohort of DLBCL cases to assess the prevalence of susceptibility effects and their clinical associations.

  • 5

    Cranial MRI scans were reviewed by experienced neuroradiologists to identify susceptibility effects and categorize morphological patterns of lesions.

Original Source(s)

Susceptibility- and T2*-weighted MRI features of CNS large B-cell lymphoma in a large single-center cohort: prevalence, patterns, and clinical associations

  • by Christophe T. Arendt, Marie Löhlau, Linda Röder, Michael C. Burger, Elke Hattingen, Stefan Weidauer

  • July 12, 2025

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