Editorial: Deciphering the microbiome's role in the progression of interstitial lung diseases - Takeaways - MDSpire

Editorial: Deciphering the microbiome's role in the progression of interstitial lung diseases

  • By

  • Roberto G. Carbone

  • Anne Marie Russell

  • June 1, 2026

  • 0 min

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  • 1

    Gut-lung microbiome dysbiosis is significantly linked to interstitial lung diseases (ILD), influencing inflammation and immune dysregulation.

  • 2

    Idiopathic pulmonary fibrosis (IPF) shows altered lung microbiome diversity, correlating with disease progression and mortality.

  • 3

    Fungal dysbiosis in sarcoidosis may serve as a biomarker, indicating the need for further research on its role in disease progression.

  • 4

    Gut dysbiosis is implicated in connective tissue-associated ILDs, with probiotics and high-fiber diets showing protective effects.

  • 5

    Traditional Chinese medicine, specifically Gand-du-quing decoction, may improve lung function by regulating lung microbiome and inflammation.

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