A Systematic Review and Meta-Analysis of the Incidence of Sensorineural Hearing Loss in Head and Neck Cancer Patients Undergoing Chemoradiotherapy Compared to Radiotherapy - Takeaways - MDSpire

A Systematic Review and Meta-Analysis of the Incidence of Sensorineural Hearing Loss in Head and Neck Cancer Patients Undergoing Chemoradiotherapy Compared to Radiotherapy

  • By

  • John Bukuru

  • Olivier Sibomana

  • January 14, 2026

  • 0 min

Share

  • 1

    Head and neck cancer (HNC) is the seventh most prevalent cancer globally, with over 660,000 new cases and 325,000 deaths annually.

  • 2

    Chemoradiotherapy is commonly used for advanced HNC, but it has a higher incidence of sensorineural hearing loss (SNHL) compared to radiotherapy alone.

  • 3

    Studies indicate that 82.5% of HNC patients undergoing chemoradiotherapy experience SNHL, compared to 25.7% with radiotherapy.

  • 4

    This systematic review aims to compare the prevalence of SNHL in HNC patients receiving chemoradiotherapy versus those receiving radiotherapy.

  • 5

    The review includes studies published from 2010 to 2025, focusing on methodological quality and specific reporting of SNHL in HNC patients.

Original Source(s)

Related Content