Long-term outcomes of endovascular thrombectomy vs. medical care in patients with large ischemic stroke: a systematic review and meta-analysis of randomized controlled trials - Takeaways - MDSpire

Long-term outcomes of endovascular thrombectomy vs. medical care in patients with large ischemic stroke: a systematic review and meta-analysis of randomized controlled trials

  • By

  • Jiayu You

  • Hang Zhou

  • Qianshuo Liu

  • Xingqiang Li

  • May 13, 2026

  • 0 min

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  • 1

    Endovascular thrombectomy (EVT) significantly improves long-term functional outcomes in patients with anterior circulation large ischemic infarcts compared to standard medical care.

  • 2

    At long-term follow-up, EVT demonstrated enhanced functional excellence, independence, and ambulation rates compared to standard medical treatment.

  • 3

    Mortality rates were not significantly different between EVT and standard medical care groups, indicating EVT's safety profile.

  • 4

    The benefits of EVT were more pronounced in patients with shorter onset times and smaller infarct volumes.

  • 5

    This systematic review emphasizes the need for refined patient selection for EVT in acute ischemic stroke management.

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