The role of albumin–globulin ratio in peripheral arterial disease among hypertensive adults: evidence from a large-scale multicenter study - Takeaways - MDSpire

The role of albumin–globulin ratio in peripheral arterial disease among hypertensive adults: evidence from a large-scale multicenter study

  • By

  • Chao Yu

  • Yang Yang

  • Xiong Liao

  • Lei Wu

  • May 28, 2026

  • 0 min

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  • 1

    The study investigates the association between albumin-globulin ratio (AGR) and peripheral arterial disease (PAD) in hypertensive adults.

  • 2

    A total of 24,808 hypertensive participants were analyzed, revealing an inverse relationship between AGR and PAD.

  • 3

    Higher AGR quartiles (Q2, Q3, Q4) were associated with reduced PAD risk compared to the lowest quartile (Q1).

  • 4

    In the fully adjusted model, the risk of PAD decreased by 35% in the highest AGR quartile compared to the lowest.

  • 5

    The association between AGR and PAD was more pronounced in individuals with a history of smoking or stroke.

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