Evaluating the Prognostic Nutritional Index, Naples Prognostic Score, and Osaka Prognostic Score for Predicting Acute Respiratory Distress Syndrome in Non-Diabetic Sepsis Patients: Diminished Predictive Value in Diabetic Populations - Takeaways - MDSpire

Evaluating the Prognostic Nutritional Index, Naples Prognostic Score, and Osaka Prognostic Score for Predicting Acute Respiratory Distress Syndrome in Non-Diabetic Sepsis Patients: Diminished Predictive Value in Diabetic Populations

  • By

  • Jie Wu

  • Wenfeng Qiu

  • Xiuwen Lin

  • Jinrun Wu

  • Renyuan Li

  • April 22, 2026

  • 0 min

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  • 1

    The study evaluated the Prognostic Nutritional Index, Naples Prognostic Score, and Osaka Prognostic Score for predicting ARDS in sepsis patients.

  • 2

    Among 2089 sepsis patients, 317 developed ARDS, with lower PNI levels and higher NPS and OPS scores in ARDS patients compared to non-ARDS patients.

  • 3

    In non-diabetic patients, low PNI, NPS scores of 3-4, and OPS scores of 2-3 were independently associated with ARDS.

  • 4

    In diabetic patients, only low PNI was associated with ARDS, while NPS and OPS did not show significant predictive value.

  • 5

    The study concluded that PNI, NPS, and OPS are effective for predicting ARDS risk in non-diabetic sepsis patients but lack efficacy in diabetic populations.

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