Bilateral double beta peaks in a PD patient with STN electrodes - Takeaways - MDSpire

Bilateral double beta peaks in a PD patient with STN electrodes

  • By

  • Thomas Koeglsperger

  • Jan H. Mehrkens

  • Kai Bötzel

  • July 24, 2020

  • 0 min

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  • 1

    Bilateral double beta peaks were observed in a Parkinson's disease patient with subthalamic nucleus electrodes during long-term local field potential recordings.

  • 2

    The patient exhibited distinct beta peaks at 15 Hz and 25 Hz, which were suppressed by stimulation and gait, with a novel 13 Hz peak emerging on the right side.

  • 3

    Deep brain stimulation significantly improved the patient's symptoms, as indicated by a reduction in UPDRS III scores from 38 to 7.

  • 4

    LFP analysis revealed that stimulation on the left side led to a gradual reduction of both beta peaks, while the right side showed a unique response to increased stimulation.

  • 5

    Gait performance monitoring indicated that stimulation completely suppressed beta peaks on the left side, while only partially suppressing them on the right side.

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