Myelodysplastic syndromes complicated by atypical Sweet syndrome: a brief research report - Takeaways - MDSpire

Myelodysplastic syndromes complicated by atypical Sweet syndrome: a brief research report

  • By

  • Bianhong Wang

  • Kun Qian

  • Hao Liu

  • Yuehua Huang

  • Yanying Wang

  • Lihong Li

  • Fan Yu

  • May 28, 2026

  • 0 min

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  • 1

    Atypical Sweet syndrome (SS) is a significant paraneoplastic dermatosis frequently associated with myelodysplastic syndromes (MDS).

  • 2

    The study analyzed three MDS patients with atypical SS, all presenting with fatigue and skin lesions before receiving MDS therapy.

  • 3

    Skin lesions in the patients were painful erythematous plaques with fever, and histopathological findings confirmed atypical SS.

  • 4

    Effective management of atypical SS in MDS requires a dual approach of systemic glucocorticoids and treatment for the underlying MDS.

  • 5

    The findings highlight the need for careful evaluation of atypical SS presentations in MDS to improve diagnosis and treatment outcomes.

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