Incomplete rather than complete nasolacrimal duct obstruction Is strongly associated with meibomian gland dysfunction in postmenopausal women with PANDO: a cross-sectional study - Takeaways - MDSpire

Incomplete rather than complete nasolacrimal duct obstruction Is strongly associated with meibomian gland dysfunction in postmenopausal women with PANDO: a cross-sectional study

  • By

  • Haili Jin

  • Yin Liu

  • Xianjie Chen

  • April 30, 2026

  • 0 min

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  • 1

    Incomplete nasolacrimal duct obstruction is significantly associated with severe meibomian gland dysfunction in postmenopausal women.

  • 2

    The study included 272 postmenopausal women, with 180 diagnosed with primary acquired nasolacrimal duct obstruction.

  • 3

    Multivariable regression analysis identified incomplete obstruction as the strongest independent risk factor for meibomian gland loss.

  • 4

    Longer duration of PANDO was linked to reduced odds of expressibility impairment in meibomian glands.

  • 5

    Routine meibography is recommended for detecting silent meibomian gland atrophy in patients with PANDO.

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