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Medical Oddities: Dogs share our mortality markers

  • By

  • Teraya Smith

  • September 2, 2026

  • 5 min

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  • 1

    Dogs share biochemical mortality markers with humans, as shown in a study analyzing 133 plasma metabolites in 937 companion dogs.

  • 2

    Seventeen percent of the metabolites studied were linked to all-cause mortality, with 23 meeting statistical significance.

  • 3

    In a follow-up period averaging 2.6 years, 104 dogs died, allowing for a quicker mortality analysis compared to human studies.

  • 4

    Mortality associations for overlapping metabolites were consistent between dogs and humans 64% of the time across five studies.

  • 5

    Specific metabolites linked to mortality in both species include higher pseudouridine and lower deoxycarnitine, indicating shared aging biology.

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