Association of serum coiled-coil domain containing protein 11 levels with coronary artery disease - Takeaways - MDSpire

Association of serum coiled-coil domain containing protein 11 levels with coronary artery disease

  • By

  • Jie Gao

  • Hongping Wang

  • Wenjun Wang

  • WenYing Hu

  • PengYong Yan

  • Jun Lu

  • ZongJun Liu

  • June 15, 2026

  • 0 min

Share

  • 1

    This study evaluated the relationship between serum CCDC11 levels and coronary artery disease (CAD) in 361 patients.

  • 2

    Median serum CCDC11 levels were significantly higher in CAD patients compared to controls, indicating a potential biomarker.

  • 3

    CCDC11 levels positively correlated with the severity of CAD, as indicated by the number of affected coronary vessels.

  • 4

    Logistic regression analysis confirmed that CCDC11 is independently associated with CAD, enhancing its clinical relevance.

  • 5

    An optimal CCDC11 cutoff value of 19.37 ng/mL was identified, with a sensitivity of 53.4% and specificity of 91.6% for CAD.

Original Source(s)

Association of serum coiled-coil domain containing protein 11 levels with coronary artery disease

  • by Jie Gao, Hongping Wang, Wenjun Wang, WenYing Hu, PengYong Yan, Jun Lu, ZongJun Liu

  • June 15, 2026

Related Content

Transcatheter patent foramen ovale closure achieves high efficacy in migraine patients: a single-center retrospective cohort study in China

Coronary endothelial cells undergo venous-enriched disrupted maturation following myocardial infarction

Proton pump inhibitor co-therapy in patients receiving non-vitamin K antagonist oral anticoagulants: current evidence, gastrointestinal bleeding prevention, and clinical considerations