Angioplasty and/or stenting after thrombectomy in patients with large vessel occlusion associated with underlying intracranial atherosclerotic stenosis: a meta-analysis and systematic review - Takeaways - MDSpire

Angioplasty and/or stenting after thrombectomy in patients with large vessel occlusion associated with underlying intracranial atherosclerotic stenosis: a meta-analysis and systematic review

  • By

  • Hesham Kelani

  • Hazem Mohamed Salamah

  • Eli Berglas

  • Emina Dzafic

  • Shivasuryan Vummidi

  • Huzaifa Dorria

  • Emily Wen Jing Shuai

  • Gitanjali Reddy

  • Desen Zeng

  • Ariel Makower

  • Dylan Davie

  • Amber Khemlani

  • Diana Greene-Chandos

  • Volodymyr Vulkanov

  • David Rosenbaum-HaLevi

  • David P. Lerner

  • Lisa R. Merlin

  • Priyank Khandelwal

  • October 16, 2025

  • 0 min

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  • 1

    Ischemic stroke, particularly due to large vessel occlusion (LVO), significantly contributes to global morbidity and mortality.

  • 2

    Mechanical thrombectomy (MT) is the gold-standard treatment for LVO caused by intracranial atherosclerotic stenosis (ICAS), but faces challenges.

  • 3

    The risk of reocclusion in ICAS-LVO patients is over 20 times higher than in those without ICAS, necessitating further treatment options.

  • 4

    This study conducted a systematic review and meta-analysis to evaluate the efficacy of MT combined with angioplasty/stenting versus MT alone.

  • 5

    The analysis included various study designs and assessed outcomes like vessel recanalization and functional independence at 90 days.

Original Source(s)

Angioplasty and/or stenting after thrombectomy in patients with large vessel occlusion associated with underlying intracranial atherosclerotic stenosis: a meta-analysis and systematic review

  • by Hesham Kelani, Hazem Mohamed Salamah, Eli Berglas, Emina Dzafic, Shivasuryan Vummidi, Huzaifa Dorria, Emily Wen Jing Shuai, Gitanjali Reddy, Desen Zeng, Ariel Makower, Dylan Davie, Amber Khemlani, Diana Greene-Chandos, Volodymyr Vulkanov, David Rosenbaum-HaLevi, David P. Lerner, Lisa R. Merlin, Priyank Khandelwal

  • October 16, 2025

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