A Socioeconomic Analysis of the Worldwide Impact of Gastroesophageal Reflux Disease (1990–2021): Insights from the GBD 2021 Study - Takeaways - MDSpire

A Socioeconomic Analysis of the Worldwide Impact of Gastroesophageal Reflux Disease (1990–2021): Insights from the GBD 2021 Study

  • By

  • Xiao Longwu

  • Xia Teng

  • November 10, 2025

  • 0 min

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  • 1

    Gastroesophageal reflux disease (GERD) affects 5% to 25% of the global population and is linked to significant health complications and economic burdens.

  • 2

    The Global Burden of Disease (GBD) database shows a 77.53% increase in global GERD cases from 1990 to 2019, highlighting a growing public health concern.

  • 3

    Geographic disparities exist in GERD prevalence, with the highest rates in Latin America and South Asia, while East Asia shows significantly lower rates.

  • 4

    Socioeconomic Development Index (SDI) is a key determinant of GERD burden, influencing risk factors like diet, obesity, and access to healthcare.

  • 5

    This study employs advanced analytical methods to explore the relationship between GERD burden and socioeconomic indicators from 1990 to 2021.

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