Antibiotic prophylaxis in stone surgery: a systematic review of the literature

1

Urolithiasis affects 1% to 20% of the global population, with a significant increase in cases over the past five decades.
2

RIRS has become a principal method for managing upper urinary tract stones but carries risks of complications, including infections.
3

Antibiotic prophylaxis is recommended for URS and PNL to reduce postoperative infections, while not recommended for SWL.
4

The systematic review included 13 studies assessing antibiotic prophylaxis in stone surgery, focusing on postoperative sepsis and UTIs.
5

Study quality assessment revealed varying risks of bias, with five studies rated low risk and three rated high risk.

World Journal Of Urology

by Filippo Gavi, Mauro Ragonese, Daniele Fettucciari, Maria Chiara Sighinolfi, Filippo Turri, Enrico Panio, Stefano Moretto, Giovanni Balocchi, Domenico Maria Sanesi, Filippo Marino, Alessandra Francocci, Pierluigi Russo, Nazario Foschi, Francesco Pinto, Emilio Sacco, Bernardo Rocco
March 3, 2025

1