Sympathetic ophthalmia induced by vitrectomy for endogenous fungal endophthalmitis: a case report and literature review - Takeaways - MDSpire

Sympathetic ophthalmia induced by vitrectomy for endogenous fungal endophthalmitis: a case report and literature review

  • By

  • Xiao-Yan Zhang

  • Jie Huang

  • Yan-E. Gao

  • Jiao Li

  • Ying Wen

  • July 7, 2026

  • 0 min

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  • 1

    Sympathetic ophthalmia (SO) is a rare inflammatory ocular disorder that can occur after ocular trauma or intraocular surgery.

  • 2

    A 22-year-old man developed SO in the contralateral eye following two vitrectomy procedures for endogenous fungal endophthalmitis.

  • 3

    The causative agent of the fungal endophthalmitis was identified as Aspergillus flavus, isolated from vitreous fluid.

  • 4

    Diagnosis of SO was supported by multimodal imaging techniques, including OCT and ICGA, despite negative fungal cultures.

  • 5

    Treatment with prednisone and adalimumab stabilized the patient's condition, with no recurrences observed during a 13-month follow-up.

Original Source(s)

Sympathetic ophthalmia induced by vitrectomy for endogenous fungal endophthalmitis: a case report and literature review

  • by Xiao-Yan Zhang, Jie Huang, Yan-E. Gao, Jiao Li, Ying Wen

  • July 7, 2026

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