Serum LRG1 as a non-invasive biomarker for identifying complex coronary anatomy in pre-angiography risk stratification - Takeaways - MDSpire

Serum LRG1 as a non-invasive biomarker for identifying complex coronary anatomy in pre-angiography risk stratification

  • By

  • Zhengkai Yang

  • Zirui Liu

  • Ying Xu

  • Haocheng Wang

  • Yu Lu

  • Cao Zou

  • June 4, 2026

  • 0 min

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  • 1

    Serum LRG1 levels are significantly elevated in acute myocardial infarction patients compared to non-AMI patients.

  • 2

    Patients with SYNTAX Scores ≥ 23 have higher serum LRG1 concentrations than those with Scores < 23.

  • 3

    LRG1 and low-density lipoprotein cholesterol are identified as independent predictors of elevated SYNTAX Score ≥ 23.

  • 4

    The logistic regression model incorporating LRG1 and LDL-C shows moderate discriminatory ability for predicting complex coronary anatomy.

  • 5

    This study suggests that serum LRG1 may serve as a non-invasive adjunct for identifying CAD patients with complex coronary anatomy.

Original Source(s)

Serum LRG1 as a non-invasive biomarker for identifying complex coronary anatomy in pre-angiography risk stratification

  • by Zhengkai Yang, Zirui Liu, Ying Xu, Haocheng Wang, Yu Lu, Cao Zou

  • June 4, 2026

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