Chronic Cough Despite Normal Workup - Takeaways - MDSpire

Chronic Cough Despite Normal Workup

Researchers describe diagnostic evaluation and management considerations when standard testing fails to identify the cause of persistent cough.

  • By

  • Kathryn Wighton

  • February 13, 2026

  • 2 min

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  • 1

    A middle-aged woman experienced a persistent dry cough for 3 months, unresponsive to inhalers or over-the-counter treatments.

  • 2

    Despite normal imaging and pulmonary function tests, her cough worsened, disrupting sleep and daily activities.

  • 3

    Flexible bronchoscopy revealed marked laryngeal hypersensitivity, a key finding in diagnosing her condition.

  • 4

    Cough-predominant laryngeal hypersensitivity syndrome is characterized by heightened laryngeal cough reflex responsiveness.

  • 5

    Management includes conservative strategies like patient education, hydration, and referral to smoking cessation programs.

Original Source(s)

Chronic Cough Despite Normal Workup

  • by Kathryn Wighton

  • February 13, 2026

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