Chronic Cough Despite Normal Workup
Researchers describe diagnostic evaluation and management considerations when standard testing fails to identify the cause of persistent cough.
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By
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Kathryn Wighton
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February 13, 2026
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1
A middle-aged woman experienced a persistent dry cough for 3 months, unresponsive to inhalers or over-the-counter treatments.
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Despite normal imaging and pulmonary function tests, her cough worsened, disrupting sleep and daily activities.
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3
Flexible bronchoscopy revealed marked laryngeal hypersensitivity, a key finding in diagnosing her condition.
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Cough-predominant laryngeal hypersensitivity syndrome is characterized by heightened laryngeal cough reflex responsiveness.
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Management includes conservative strategies like patient education, hydration, and referral to smoking cessation programs.