Aspirin Use for Secondary Prevention Amid Negative Messaging in Patients With Cardiovascular Disease - Takeaways - MDSpire

Aspirin Use for Secondary Prevention Amid Negative Messaging in Patients With Cardiovascular Disease

  • By

  • Jeremy R. Van’t Hof

  • Sue Duval

  • Niki Oldenburg

  • Milton Eder

  • Russell V. Luepker

  • June 4, 2026

  • 0 min

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  • 1

    Aspirin is recommended for secondary prevention of ASCVD, but primary prevention use has declined due to increased bleeding risks and negative public perceptions.

  • 2

    The Ask About Aspirin project surveyed 1890 participants with ASCVD from 2015 to 2020, revealing stable aspirin use for secondary prevention during this period.

  • 3

    Conversations with physicians significantly reduced the likelihood of stopping aspirin, with 65.9% of stoppers citing physician recommendations as the reason.

  • 4

    Despite negative messaging about aspirin for primary prevention, only 1.8% of aspirin stoppers attributed their cessation to these messages.

  • 5

    The study highlights the importance of patient-clinician trust and communication in maintaining adherence to aspirin therapy amid evolving guidelines.

Original Source(s)

Aspirin Use for Secondary Prevention Amid Negative Messaging in Patients With Cardiovascular Disease

  • by Jeremy R. Van’t Hof, Sue Duval, Niki Oldenburg, Milton Eder, Russell V. Luepker

  • June 4, 2026

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