The impact of menstrual cycle phases on postoperative nausea and vomiting in premenopausal women undergoing laparoscopic gastrointestinal surgery: a secondary analysis of a randomized controlled trial - Takeaways - MDSpire

The impact of menstrual cycle phases on postoperative nausea and vomiting in premenopausal women undergoing laparoscopic gastrointestinal surgery: a secondary analysis of a randomized controlled trial

  • By

  • Chujun Liang

  • Xuemei Song

  • Chuling Liu

  • July 7, 2026

  • 0 min

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  • 1

    The study analyzed the effect of menstrual cycle phases on postoperative nausea and vomiting (PONV) in premenopausal women after laparoscopic gastrointestinal surgery.

  • 2

    A total of 240 women participated, with 119 in the non-luteal phase and 121 in the luteal phase, showing no significant difference in PONV incidence.

  • 3

    PONV rates during the first 24 hours post-surgery were 44.5% in the non-luteal group and 47.1% in the luteal group, with an adjusted odds ratio of 1.10.

  • 4

    Sensitivity analyses indicated no significant association between surgery-to-ovulation interval or menstrual cycle phase and PONV outcomes.

  • 5

    The study concluded that menstrual cycle phase does not influence the occurrence of PONV in premenopausal women undergoing the specified surgery.

Original Source(s)

The impact of menstrual cycle phases on postoperative nausea and vomiting in premenopausal women undergoing laparoscopic gastrointestinal surgery: a secondary analysis of a randomized controlled trial

  • by Chujun Liang, Xuemei Song, Chuling Liu

  • July 7, 2026

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