Implementation of Exclusive Enteral Nutrition in Pediatric Crohn's Disease: A Secondary Analysis of the CLARA Registry Study

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Exclusive enteral nutrition (EEN) is the first-line therapy for children with active luminal Crohn's disease.
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The study analyzed data from 319 children, comparing intervention and control groups regarding enteral nutrition use.
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A non-significant trend toward higher enteral nutrition use was observed in the intervention group compared to the control group.
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EEN for the recommended duration was uncommon, with only 9.5% in the intervention group and 18.8% in the control group.
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Steroid use within 90 days was significantly higher in the control group compared to the intervention group.

Frontiers In Pediatrics

by Tischler, Luisa , Boerkoel, Aletta , Cantez, Mustafa Serdar, Krause, Heiko , De Laffolie, Jan , van den Berg, Neeltje
May 4, 2026

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