Link Between Estimated Glucose Disposal Rate and Overall as well as Breast Cancer-Specific Mortality in Survivors: A Population-Based Analysis in the United States - Takeaways - MDSpire

Link Between Estimated Glucose Disposal Rate and Overall as well as Breast Cancer-Specific Mortality in Survivors: A Population-Based Analysis in the United States

  • By

  • Jinhao Li

  • Jiasheng Liu

  • Bingliang Cai

  • Chuansheng Yang

  • November 27, 2025

  • 0 min

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  • 1

    Breast cancer is the leading cancer among women, accounting for a significant proportion of cancer cases and deaths globally.

  • 2

    Insulin resistance (IR) is a critical factor in breast cancer progression and prognosis, particularly affecting patients undergoing endocrine therapy.

  • 3

    The estimated glucose disposal rate (eGDR) serves as a reliable, non-invasive marker for assessing insulin sensitivity in large epidemiological studies.

  • 4

    This study investigates the association between eGDR and breast cancer prevalence, focusing on its impact on all-cause mortality among survivors.

  • 5

    Findings aim to identify high-risk breast cancer survivors and inform targeted metabolic interventions to improve long-term survival outcomes.

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