Detection of prostate cancer with 18F-DCFPyL PET/CT compared to final histopathology of radical prostatectomy specimens: is PSMA-targeted biopsy feasible? The DeTeCT trial - Takeaways - MDSpire

Detection of prostate cancer with 18F-DCFPyL PET/CT compared to final histopathology of radical prostatectomy specimens: is PSMA-targeted biopsy feasible? The DeTeCT trial

  • By

  • Y. J. L. Bodar

  • B. H. E. Jansen

  • J. P. van der Voorn

  • G. J. C. Zwezerijnen

  • D. Meijer

  • J. A. Nieuwenhuijzen

  • R. Boellaard

  • N. H. Hendrikse

  • O. S. Hoekstra

  • R. J. A. van Moorselaar

  • D. E. Oprea-Lager

  • A. N. Vis

  • October 20, 2020

  • 0 min

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  • 1

    Prostate cancer is the most prevalent cancer in men in the Western world, necessitating accurate diagnostic methods for effective management.

  • 2

    Histopathological verification through systematic biopsies is standard, but these can yield false negatives due to sampling errors.

  • 3

    18F-DCFPyL PET/CT imaging shows high accuracy in detecting primary prostate tumors, with detection rates between 98-100%.

  • 4

    The DeTeCT trial aims to evaluate the feasibility of PSMA-targeted biopsy using 18F-DCFPyL PET/CT compared to histopathology.

  • 5

    The study's results could enhance targeted biopsy recommendations and improve local tumor staging in prostate cancer patients.

Original Source(s)

Detection of prostate cancer with 18F-DCFPyL PET/CT compared to final histopathology of radical prostatectomy specimens: is PSMA-targeted biopsy feasible? The DeTeCT trial

  • by Y. J. L. Bodar, B. H. E. Jansen, J. P. van der Voorn, G. J. C. Zwezerijnen, D. Meijer, J. A. Nieuwenhuijzen, R. Boellaard, N. H. Hendrikse, O. S. Hoekstra, R. J. A. van Moorselaar, D. E. Oprea-Lager, A. N. Vis

  • October 20, 2020

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