Adjuvant radiotherapy for WHO grade II meningiomas: the unanswered question

1

WHO grade II meningiomas exhibit high recurrence rates and aggressive behavior, necessitating careful management post-surgery.
2

This study analyzed 318 patients with WHO grade II meningiomas to evaluate the impact of adjuvant radiotherapy on survival outcomes.
3

Adjuvant radiotherapy was associated with significantly reduced progression-free survival and cause-specific survival in both resection groups.
4

Stereotactic fractionated conformal radiotherapy and radiosurgery were identified as independent predictors of recurrence and mortality.
5

The findings challenge existing treatment paradigms and highlight the need for personalized approaches and further prospective studies.