Fetal growth in PCOS pregnancies: dynamic evidence of restriction and the modifying role of ART - Takeaways - MDSpire

Fetal growth in PCOS pregnancies: dynamic evidence of restriction and the modifying role of ART

  • By

  • Heze Xu

  • Yijia Liu

  • Xinyi Bian

  • Zhijiao Wang

  • Zhen Li

  • Hang Zhen

  • Shanwei Xing

  • Jingshuang Zhou

  • Zekai Bai

  • Jiapo Li

  • Chong Qiao

  • July 15, 2026

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  • 1

    Polycystic ovary syndrome (PCOS) is linked to adverse pregnancy outcomes, including fetal growth restriction and lower birth weight.

  • 2

    In a study of 12,189 pregnancies, PCOS fetuses exhibited reduced second and third trimester Z-scores for various growth parameters.

  • 3

    Fetal growth restriction in PCOS pregnancies was evident from the second trimester and persisted until delivery.

  • 4

    Assisted reproductive technology (ART) appeared to mitigate fetal growth restriction in PCOS pregnancies compared to spontaneous conceptions.

  • 5

    The study emphasizes the need for dynamic ultrasound monitoring in PCOS pregnancies to optimize management and perinatal outcomes.

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