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Medical Oddities: A broken heart courtesy of the flu

  • By

  • Teraya Smith

  • November 12, 2026

  • 6 min

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  • 1

    A 67-year-old woman developed Takotsubo cardiomyopathy 2 weeks after testing positive for influenza A.

  • 2

    Despite ECG changes, elevated troponin I, and a left ventricular ejection fraction of 30%, catheterization showed nonobstructive coronary artery disease.

  • 3

    Left ventriculography showed severe apical hypokinesis with hyperdynamic basal segments, characteristic of Takotsubo cardiomyopathy.

  • 4

    She initially received aspirin, clopidogrel, and intravenous heparin, then was discharged on a statin and an angiotensin-converting enzyme inhibitor with prompt cardiology follow-up.

  • 5

    Potential Takotsubo cardiomyopathy complications include heart failure, cardiogenic shock, arrhythmias, and thrombosis.

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