Efficacy and Safety of Vitamin D in the Treatment of Asthma: An Overview of Systematic Reviews and Meta-Analyses

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Vitamin D supplementation may reduce the risk of asthma exacerbations as an adjunctive treatment.
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The effects of vitamin D on asthma control, lung function, and inflammatory outcomes are limited or inconsistent.
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No significant increase in adverse events was observed with vitamin D supplementation in asthma patients.
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The certainty of evidence regarding vitamin D's efficacy in asthma management varies and is often low.
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Future research should focus on identifying patients who benefit most and optimizing vitamin D supplementation strategies.

Frontiers In Medicine

by Liu, Yongxiu , Lu, Jiaheng , Li, Donghao , Wang, Zhuang , Zhang, Chi , Li, Yuguo , Liang, Shuang , Yang, Haimiao , Gao, Lei
May 6, 2026

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