Hepatitis B Core-Related Antigen Point-of-Care Tests as a Risk Stratification Tool for Treatment Eligibility: Experience From Kenya - Takeaways - MDSpire

Hepatitis B Core-Related Antigen Point-of-Care Tests as a Risk Stratification Tool for Treatment Eligibility: Experience From Kenya

  • By

  • Louise O Downs

  • Dorcas Okanda

  • Oscar Chirro

  • Mwanakombo Zaharani

  • Benson Safari

  • Nadia Aliyan

  • Monique I Andersson

  • Yasuhito Tanaka

  • Anthony O Etyang

  • Yusuke Shimakawa

  • George Githinji

  • Philippa C Matthews

  • March 6, 2025

  • 0 min

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  • 1

    A point-of-care test for hepatitis B core-related antigen (HBcrAg) was evaluated in adults with hepatitis B virus in Kilifi, Kenya.

  • 2

    The HBcrAg test identified individuals with high viral loads and correlated with elevated ALT levels and liver stiffness scores.

  • 3

    Only 0.2% of people with hepatitis B in the WHO African Region are on treatment, highlighting a significant barrier to HBV elimination.

  • 4

    The HBcrAg point-of-care test showed a 91.4% sensitivity and 86.3% specificity for detecting high HBV viral loads.

  • 5

    The study suggests that HBcrAg testing could improve treatment eligibility assessment in resource-limited settings.

Original Source(s)

Hepatitis B Core-Related Antigen Point-of-Care Tests as a Risk Stratification Tool for Treatment Eligibility: Experience From Kenya

  • by Louise O Downs, Dorcas Okanda, Oscar Chirro, Mwanakombo Zaharani, Benson Safari, Nadia Aliyan, Monique I Andersson, Yasuhito Tanaka, Anthony O Etyang, Yusuke Shimakawa, George Githinji, Philippa C Matthews

  • March 6, 2025

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