Zygosity and autonomic stress reactivity during social exclusion: biofeedback findings from the TwinCord-EDID study - Takeaways - MDSpire

Zygosity and autonomic stress reactivity during social exclusion: biofeedback findings from the TwinCord-EDID study

  • By

  • Anna Zalpur

  • Nazar Mazurak

  • Sophia Kristina Wolf

  • Katja Weimer

  • Jeannette Hübener-Schmid

  • Miriam Goebel-Stengel

  • Stephan Zipfel

  • Andreas Stengel

  • June 24, 2026

  • 0 min

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  • 1

    The study examined autonomic responses to social exclusion in twins with and without symptoms of functional gastrointestinal disorders and eating disorders.

  • 2

    Participants included 35 monozygotic and dizygotic twin pairs, with zygosity confirmed through genetic blood testing.

  • 3

    Heart rate variability, skin conductance, skin temperature, and subjective stress ratings were assessed during a controlled social exclusion task.

  • 4

    Results indicated significant changes in physiological and subjective stress responses across experimental phases, but no differences between symptom groups.

  • 5

    Exploratory analyses suggested that both genetic and environmental factors may influence individual differences in stress reactivity.

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