Effects of ketogenic diet therapy in outpatient anti epileptic drug cost reduction and parental satisfaction among children with intractable epilepsy - Takeaways - MDSpire

Impact of Ketogenic Diet Therapy on Reducing Outpatient Anti-Epileptic Medication Costs and Enhancing Parental Satisfaction in Children with Drug-Resistant Epilepsy

  • By

  • Achmad Rafli

  • Setyo Handryastuti

  • Amanda Soebadi

  • Dara Ninggar Santoso

  • Indira Rahmawati

  • Ryan Pramana

  • Rahadian Ramadhan

  • Clifford Peter Anthony

  • Irawan Mangunatmadja

  • July 17, 2026

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  • 1

    Approximately 11 million children worldwide suffer from epilepsy, with 25-30% developing drug-resistant epilepsy (DRE).

  • 2

    The study evaluated the cost of anti-epileptic drugs before and after 6 months of ketogenic diet therapy (KDT) in children with DRE.

  • 3

    Incorporating KDT resulted in a statistically significant 21.8% reduction in outpatient anti-epileptic drug costs among 16 patients.

  • 4

    The average cost reduction amounted to Rp 3,757,812 or 235 US$ after 6 months of KDT.

  • 5

    Parents reported satisfaction with KDT, indicating its potential benefits beyond just financial savings.

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