Comparative Analysis of the Efficacy and Safety of PreserFlo MicroShunt and Trabeculectomy in Glaucoma Management: A Systematic Review, Meta-Analysis, and Meta-Regression of Clinical Outcomes and Influencing Factors - Takeaways - MDSpire
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Comparative Analysis of the Efficacy and Safety of PreserFlo MicroShunt and Trabeculectomy in Glaucoma Management: A Systematic Review, Meta-Analysis, and Meta-Regression of Clinical Outcomes and Influencing Factors

  • By

  • Yousef Mesaed Al-Shammari

  • Abdulaziz Alotaibi

  • Basel Bader Alkharraz

  • Saddik Haddad

  • Hasan Alshawaf

  • March 19, 2026

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  • 1

    Glaucoma is a major cause of irreversible blindness, with intraocular pressure (IOP) reduction being the only modifiable risk factor.

  • 2

    Trabeculectomy is the most common glaucoma surgery, effective in lowering IOP but associated with significant postoperative complications.

  • 3

    The PreserFlo MicroShunt represents a minimally invasive surgical option aimed at reducing risks compared to traditional trabeculectomy.

  • 4

    This systematic review and meta-analysis evaluated the efficacy and safety of PreserFlo MicroShunt versus trabeculectomy in glaucoma patients.

  • 5

    Primary outcomes included postoperative IOP, IOP reduction, surgical success rates, and safety outcomes such as postoperative complications.

Original Source(s)

Comparative Analysis of the Efficacy and Safety of PreserFlo MicroShunt and Trabeculectomy in Glaucoma Management: A Systematic Review, Meta-Analysis, and Meta-Regression of Clinical Outcomes and Influencing Factors

  • by Yousef Mesaed Al-Shammari, Abdulaziz Alotaibi, Basel Bader Alkharraz, Saddik Haddad, Hasan Alshawaf

  • March 19, 2026

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