Epidemiology, determinants, and microbiological profile of implant-associated infections following intramedullary nailing in a tertiary hospital in Ethiopia - Takeaways - MDSpire
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Epidemiology, Risk Factors, and Microbial Characteristics of Infections After Intramedullary Nailing at a Tertiary Hospital in Ethiopia

  • By

  • Abebaw Muhabaw Zegeye

  • Suleiman Ayalew Belay

  • Ephrem Bekele Kebede

  • Birlew Teshome Alemayehu

  • Sileshi Serebe Zeleke

  • Yohannis Derbew Molla

  • October 14, 2026

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  • 1

    This cross-sectional study at a tertiary hospital in Ethiopia assessed infections after femoral or tibial intramedullary nailing performed from 2021 through 2023.

  • 2

    Of 295 identified patients, 260 were included in the analysis after exclusions for pathological fractures, referral after surgery elsewhere, and incomplete registry data.

  • 3

    The study aimed to quantify implant-associated infections, identify associated patient, injury, and perioperative factors, and characterize pathogens and antimicrobial resistance.

  • 4

    Surgeons documented implant-associated infection using criteria established by Metsemakers et al.

  • 5

    Perioperative antibiotic prophylaxis followed Ethiopian guidelines, with regimens varying by fracture type and, for open fractures, Gustilo-Anderson grade.

Original Source(s)

Epidemiology, determinants, and microbiological profile of implant-associated infections following intramedullary nailing in a tertiary hospital in Ethiopia

  • by Abebaw Muhabaw Zegeye, Suleiman Ayalew Belay, Ephrem Bekele Kebede, Birlew Teshome Alemayehu, Sileshi Serebe Zeleke, Yohannis Derbew Molla

  • October 14, 2026

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