Editorial: Psychosocial factors, mental comorbidities and related biomarkers interacting with the onset and course of somatic diseases - Takeaways - MDSpire
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Editorial: The Interplay of Psychosocial Elements, Mental Health Comorbidities, and Associated Biomarkers in the Development and Progression of Physical Illnesses

  • By

  • Gloria-Beatrice Wintermann

  • Michael Noll-Hussong

  • September 15, 2026

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  • 1

    Psychosocial and mental health factors significantly influence the development and progression of chronic somatic diseases.

  • 2

    Comorbid mental disorders can complicate treatment adherence and worsen overall quality of life in patients with physical illnesses.

  • 3

    Lifestyle behaviors and emotional support are critical moderators affecting clinical outcomes in patients with chronic diseases.

  • 4

    Major depressive disorder is associated with increased risk of sepsis, highlighting the need for clinical awareness in affected patients.

  • 5

    Positive psychological well-being is linked to lower cardiovascular disease risk and improved health-related quality of life.

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