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1
Neuroinfectious diseases pose significant global health challenges, leading to high morbidity and mortality despite antimicrobial advancements.
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2
Host-mediated immune responses play a crucial role in neurological outcomes, prompting interest in host-directed therapies (HDTs) to modulate these responses.
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3
Acupuncture has emerged as a potential non-pharmacological HDT, showing promise in modulating inflammatory signaling and neuroimmune functions.
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4
Current evidence for acupuncture's efficacy in neuroinfectious diseases is limited, primarily derived from non-infectious models requiring cautious interpretation.
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5
Further systematic investigation is warranted to explore acupuncture's therapeutic potential in neuroinfectious diseases, given its plausible neuroimmune regulatory effects.