Diagnostic value of cardiovascular biomarkers for cerebral–cardiac syndrome risk in acute ischemic stroke

1

Cerebral–cardiac syndrome (CCS) is a common complication after ischemic stroke, leading to increased morbidity and mortality.
2

The study analyzed 177 acute ischemic stroke patients to evaluate cardiovascular biomarkers for diagnosing CCS.
3

BNP, D-Dimer, cTnI, Myo, and CK-MB levels were significantly higher in CCS patients compared to non-CCS patients.
4

Age, BNP, and Myo were identified as independent risk factors for CCS, with a robust diagnostic model showing excellent discriminatory ability.
5

The findings support the need for early identification of CCS to facilitate timely risk stratification and intervention in acute ischemic stroke patients.

Frontiers In Medicine

by Zegang Liu, Ying Zhao, Mei Wang, Chenwei Li, Xurong Zhu, Peirui Wang, Ke Wang
July 8, 2026

1