Pulsed field ablation vs. medical therapy for atrial fibrillation: a propensity score–matched comparison with the JoFib registry - Takeaways - MDSpire

Pulsed field ablation vs. medical therapy for atrial fibrillation: a propensity score–matched comparison with the JoFib registry

  • By

  • Abdalrahman Al-slaimieh

  • Khaled A. Abukhalaf

  • Nour S. Haj Ali

  • Jude Awad

  • Abdallah Al-Ani

  • Ayman J. Hammoudeh

  • Mohammad Hajjiri

  • June 5, 2026

  • 0 min

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  • 1

    Pulsed field ablation (PFA) is a novel, non-thermal method for treating atrial fibrillation (AF) that shows promise compared to medical therapy.

  • 2

    In a study of 62 patients, PFA demonstrated significantly lower readmission rates for AF recurrence or heart failure than matched medical therapy patients.

  • 3

    The 1-month and 6-month readmission rates for the PFA cohort were 3.2% and 4.8%, compared to 12.9% and 17.7% for the medical therapy cohort.

  • 4

    Kaplan-Meier analysis indicated a higher freedom from readmission in the PFA group, with rates of 92% versus 69% in the medical therapy group.

  • 5

    This study supports the efficacy of PFA for AF treatment and sets the stage for larger future studies in the MENA region.

Original Source(s)

Pulsed field ablation vs. medical therapy for atrial fibrillation: a propensity score–matched comparison with the JoFib registry

  • by Abdalrahman Al-slaimieh, Khaled A. Abukhalaf, Nour S. Haj Ali, Jude Awad, Abdallah Al-Ani, Ayman J. Hammoudeh, Mohammad Hajjiri

  • June 5, 2026

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