Case report: When Behçet’s disease meets multizonal outer retinopathy and retinal pigment epitheliopathy: longitudinal multimodal imaging of an overlap phenotype - Takeaways - MDSpire
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Case Study: Documenting the Intersection of Behçet’s Disease with Multizonal Outer Retinopathy and Retinal Pigment Epitheliopathy through Longitudinal Multimodal Imaging

  • By

  • Jiang Jikuan

  • Cheng Yizhe

  • Chen Chunli

  • June 12, 2026

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  • 1

    A 37-year-old male with Behçet’s disease presented with unilateral, painless, progressive vision loss and recurrent oral ulcers.

  • 2

    Longitudinal multimodal imaging revealed bilateral outer retinopathy and retinal vasculitis, indicating an acute progressive episode.

  • 3

    The diagnosis of multizonal outer retinopathy and retinal pigment epitheliopathy (MORR) complicated by Behçet’s uveitis was established.

  • 4

    Systemic treatment with corticosteroids and cyclosporine resulted in stable lesions at three-month follow-up, with subtle progression at nine months.

  • 5

    This case emphasizes the need for multimodal imaging in Behçet’s disease and highlights the potential for concurrent outer retinopathy.

Original Source(s)

Case report: When Behçet’s disease meets multizonal outer retinopathy and retinal pigment epitheliopathy: longitudinal multimodal imaging of an overlap phenotype

  • by Jiang Jikuan, Cheng Yizhe, Chen Chunli

  • June 12, 2026

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