Physician-led versus questionnaire-based psychosocial screening in adults with high-grade glioma: a cluster-randomized controlled trial (GLIOPT) - Takeaways - MDSpire

Physician-led versus questionnaire-based psychosocial screening in adults with high-grade glioma: a cluster-randomized controlled trial (GLIOPT)

  • By

  • Mirjam Renovanz

  • Melina Hippler

  • Robert Kuchen

  • Lorenz Doerner

  • David Rieger

  • Joachim P. Steinbach

  • Michael W. Ronellenfitsch

  • Martin Voss

  • Almuth F. Kessler

  • Vera Nickl

  • Martin Misch

  • Julia Sophie Onken

  • Marion Rapp

  • Minou Nadji-Ohl

  • Marcus Mehlitz

  • Jürgen Meixensberger

  • Michael Karl Fehrenbach

  • Naureen Keric

  • Florian Ringel

  • Jan Coburger

  • Carolin Weiß Lucas

  • Jens Wehinger

  • Friederike Schmidt-Graf

  • Jens Gempt

  • Marcos Tatagiba

  • Ghazaleh Tabatabai

  • Melanie Schranz

  • Susanne Singer

  • September 10, 2025

  • 0 min

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  • 1

    High-grade glioma is the most common primary brain tumor, with survival rates varying significantly between glioblastoma and oligodendroglioma patients.

  • 2

    Patients with high-grade gliomas face substantial symptom burdens, including neurological deficits and psychiatric comorbidities like depression and anxiety.

  • 3

    The GLIOPT trial aimed to improve psychosocial distress identification by integrating screening questions into doctor-patient consultations.

  • 4

    The study compared two approaches: face-to-face psychosocial assessments during consultations and standard care using the NCCN Distress Thermometer.

  • 5

    Results will help determine the effectiveness of direct assessments in enhancing psychosocial support for high-grade glioma patients.

Original Source(s)

Physician-led versus questionnaire-based psychosocial screening in adults with high-grade glioma: a cluster-randomized controlled trial (GLIOPT)

  • by Mirjam Renovanz, Melina Hippler, Robert Kuchen, Lorenz Doerner, David Rieger, Joachim P. Steinbach, Michael W. Ronellenfitsch, Martin Voss, Almuth F. Kessler, Vera Nickl, Martin Misch, Julia Sophie Onken, Marion Rapp, Minou Nadji-Ohl, Marcus Mehlitz, Jürgen Meixensberger, Michael Karl Fehrenbach, Naureen Keric, Florian Ringel, Jan Coburger, Carolin Weiß Lucas, Jens Wehinger, Friederike Schmidt-Graf, Jens Gempt, Marcos Tatagiba, Ghazaleh Tabatabai, Melanie Schranz, Susanne Singer

  • September 10, 2025

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