Exploratory Study of Bioactive Adrenomedullin as a Potential Biomarker for Severe Infections in Emergency Department Patients - Takeaways - MDSpire

Exploratory Study of Bioactive Adrenomedullin as a Potential Biomarker for Severe Infections in Emergency Department Patients

  • By

  • Constantin Maier-Stocker

  • Julian Hupf

  • Jillena Zinsser-Krys

  • Markus Zimmermann

  • Frank Hanses

  • February 28, 2026

  • 0 min

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  • 1

    Bioactive adrenomedullin (bio-ADM) is a promising biomarker for diagnosing severe infections and sepsis in emergency department patients.

  • 2

    Elevated bio-ADM levels correlate with increased mortality, multi-organ failure, and ICU admissions in patients with suspected severe infections.

  • 3

    Point-of-care testing for bio-ADM can provide rapid results, aiding in the timely diagnosis and management of sepsis in emergency settings.

  • 4

    The study aimed to evaluate the predictive capability of bio-ADM for bacteremia in patients presenting with suspected severe infections.

  • 5

    Previous research indicates that bio-ADM may outperform traditional biomarkers like CRP and lactate in predicting 28-day mortality in sepsis.

Original Source(s)

Exploratory Study of Bioactive Adrenomedullin as a Potential Biomarker for Severe Infections in Emergency Department Patients

  • by Constantin Maier-Stocker, Julian Hupf, Jillena Zinsser-Krys, Markus Zimmermann, Frank Hanses

  • February 28, 2026

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