Preoperative and early postoperative albumin thresholds, rather than ΔAlb, predict severe complications after colorectal cancer surgery: a multifactorial model and nomogram - Takeaways - MDSpire

Preoperative and early postoperative albumin thresholds, rather than ΔAlb, predict severe complications after colorectal cancer surgery: a multifactorial model and nomogram

  • By

  • Lu Wang

  • Rui-Rui Lyu

  • Yue Ding

  • Ze-Qing Gao

  • Li-Qin Deng

  • July 13, 2026

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  • 1

    Severe complications occurred in 14.2% of 932 colorectal cancer surgery patients analyzed in this study.

  • 2

    ΔAlb showed no significant association with severe complications, indicating limited predictive value.

  • 3

    Preoperative albumin <35 g/L and POD2 nadir albumin <28.5 g/L were identified as independent risk factors for severe complications.

  • 4

    Other independent predictors included age >65 years, ASA ≥3, preoperative NRS2002 ≥2, and rocuronium dose ≥117.5 mg.

  • 5

    A nomogram integrating these factors demonstrated good discrimination and calibration for predicting severe complications.

Original Source(s)

Preoperative and early postoperative albumin thresholds, rather than ΔAlb, predict severe complications after colorectal cancer surgery: a multifactorial model and nomogram

  • by Lu Wang, Rui-Rui Lyu, Yue Ding, Ze-Qing Gao, Li-Qin Deng

  • July 13, 2026

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