Adolescent Girls With Type 1 Diabetes Develop Changes in Bone Prior to Evidence of Clinical Neuropathy - Takeaways - MDSpire

Adolescent Girls With Type 1 Diabetes Develop Changes in Bone Prior to Evidence of Clinical Neuropathy

  • By

  • Ivana Shen

  • Rachel L Usala

  • Mahshid Mohseni

  • Mary L Bouxsein

  • Deborah M Mitchell

  • Erica L Scheller

  • July 26, 2024

  • 0 min

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  • 1

    Adolescent girls with type 1 diabetes (T1D) exhibit significant early deficits in trabecular bone microarchitecture compared to controls.

  • 2

    Participants with T1D showed decreased trabecular bone volume fraction and thickness at both the distal radius and tibia.

  • 3

    Cortical bone mineral density in the tibia was increased in T1D participants, alongside decreased porosity.

  • 4

    Lower circulating levels of osteocalcin and type I collagen cross-linked C-telopeptide indicate suppressed bone formation in T1D.

  • 5

    The study highlights the need for early detection and management strategies for bone health in adolescents with T1D.

Original Source(s)

Adolescent Girls With Type 1 Diabetes Develop Changes in Bone Prior to Evidence of Clinical Neuropathy

  • by Ivana Shen, Rachel L Usala, Mahshid Mohseni, Mary L Bouxsein, Deborah M Mitchell, Erica L Scheller

  • July 26, 2024

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