Non-tobacco nicotine dependence is associated with increased complications following clavicle open reduction internal fixation - Takeaways - MDSpire

Non-tobacco nicotine dependence is associated with increased complications following clavicle open reduction internal fixation

  • By

  • Akin A. Adio

  • Rahul K. Goyal

  • Abby Skiena

  • Mohammad Daher

  • John G. Horneff

  • Hafiz F. Kassam

  • Brian W. Hill

  • Joseph A. Abboud

  • June 18, 2026

  • 0 min

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  • 1

    Clavicle fractures account for 2.6-5% of adult fractures, with surgical fixation rates increasing significantly from 2000 to 2022.

  • 2

    Non-tobacco nicotine dependence is rising, especially among adolescents, despite misconceptions about its safety compared to traditional tobacco.

  • 3

    This study investigates the impact of non-tobacco nicotine dependence on complication rates after open reduction and internal fixation of clavicle fractures.

  • 4

    Patients with non-tobacco nicotine dependence may experience higher complication rates, including infection and nonunion, after clavicle surgery.

  • 5

    The study utilizes a retrospective cohort design, analyzing data from the TriNetX database to assess postoperative outcomes related to nicotine exposure.

Original Source(s)

Non-tobacco nicotine dependence is associated with increased complications following clavicle open reduction internal fixation

  • by Akin A. Adio, Rahul K. Goyal, Abby Skiena, Mohammad Daher, John G. Horneff, Hafiz F. Kassam, Brian W. Hill, Joseph A. Abboud

  • June 18, 2026

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