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1
Cytokine-induced killer (CIK) cell therapy shows promising antitumor effects in gastric cancer, warranting a systematic review and meta-analysis.
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2
The meta-analysis included 22 trials with 2,149 patients, assessing the safety and efficacy of CIK/DC-CIK therapy combined with chemotherapy.
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3
Pooled hazard ratios indicated significant improvements in overall survival, progression-free survival, and disease-free survival with CIK therapy.
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4
Immunological analyses revealed increased T cell subsets, while fever was the most common adverse event, with no fatal events reported.
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5
All included studies were conducted in China, highlighting the need for validation in more diverse populations to confirm findings.
