Clinical trial set to test two drugs for fast-growing Ebola outbreak - Takeaways - MDSpire

Clinical trial set to test two drugs for fast-growing Ebola outbreak

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  • Helen Branswell

  • June 24, 2026

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  • 1

    A clinical trial will test Gilead's remdesivir and MappBio's MBP-134 against the Bundibugyo ebolavirus in the Democratic Republic of the Congo.

  • 2

    The trial aims to determine the effectiveness of the therapies individually and in combination during the current Ebola outbreak.

  • 3

    The outbreak in the DRC is the third largest on record, with nearly 1,100 confirmed cases and over 275 deaths reported.

  • 4

    The U.S. government has supplied doses of MBP-134 for the trial, while Gilead has provided doses of remdesivir.

  • 5

    The trial will require approximately 1,000 participants due to the lower case fatality rate associated with the Bundibugyo species of Ebola.

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