Exploring the relationship between novel serum inflammatory markers, non-traditional lipid parameters, and in-stent restenosis after percutaneous coronary intervention: a single-center retrospective study - Takeaways - MDSpire
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Investigating the association of innovative serum inflammatory markers and atypical lipid profiles with in-stent restenosis following percutaneous coronary intervention: a retrospective analysis from a single center

  • By

  • Mingliang Du

  • Miao Jiang

  • Hui Hui

  • July 9, 2026

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  • 1

    In-stent restenosis (ISR) remains a significant cause of failure in percutaneous coronary intervention (PCI) despite advancements in drug-eluting stents (DES).

  • 2

    The study analyzed 564 patients, identifying 112 with ISR and 452 without, to investigate inflammatory indices and lipid parameters associated with ISR.

  • 3

    Higher levels of CRI-II and LCI were found in the ISR group, with CRI-II and LCI identified as independent risk factors for ISR after adjustment.

  • 4

    Receiver operating characteristic analysis indicated that CRI-II and LCI had limited discriminatory ability for predicting ISR, with AUC values below 0.7.

  • 5

    The study concludes that while CRI-II and LCI show statistical associations with ISR, they are not ready for clinical recommendation in risk stratification.

Original Source(s)

Exploring the relationship between novel serum inflammatory markers, non-traditional lipid parameters, and in-stent restenosis after percutaneous coronary intervention: a single-center retrospective study

  • by Mingliang Du, Miao Jiang, Hui Hui

  • July 9, 2026

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